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Demonstration of the Chiral Inversion of 2-Phenylpropionic Acid by Cell Extracts from Verticillium lecanii

✍ Scribed by W. Rhys-Williams; M. J. Thomason; A. W. Lloyd; G. W. Hanlon


Book ID
118109972
Publisher
Pharmaceutical Press
Year
1996
Tongue
English
Weight
535 KB
Volume
2
Category
Article
ISSN
2042-7158

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Previous investigations have described the development of nongrowing suspensions of Verticillium lecanii as a microbial model of the mammalian chiral inversion of the 2-arylpropionic acids (2-APAs). Mechanistic studies in mammals have shown that inversion involves loss of the ␣-methine proton but re