Optimization of a Dihydropyrrolopyrazole Series of Transforming Growth Factor-β Type I Receptor Kinase Domain Inhibitors: Discovery of an Orally Bioavailable Transforming Growth Factor-β Receptor Type I Inhibitor as Antitumor Agent

✍ Scribed by Li, Hong-yu; McMillen, William T.; Heap, Charles R.; McCann, Denis J.; Yan, Lei; Campbell, Robert M.; Mundla, Sreenivasa R.; King, Chi-Hsin R.; Dierks, Elizabeth A.; Anderson, Bryan D.; Britt, Karen S.; Huss, Karen L.; Voss, Matthew D.; Wang, Yan; Clawson, David K.; Yingling, Jonathan M.; Sawyer, J. Scott

• Book ID: 120450920
• Publisher: American Chemical Society
• Year: 2008
• Tongue: English
• Weight: 424 KB
• Volume: 51
• Category: Article
• ISSN: 0022-2623
• DOI: 10.1021/jm701199p