## Abstract A five‐step synthesis of the neonicotinoid insecticide imidacloprid (**1**) labelled with ^15^N is reported in an overall yield of 10%. The stable isotope ^15^N was introduced in the pyridine part by reaction of ^15^NH~3~ with coumalic acid methyl ester (**2**) to ^15^__N__‐hydroxy nico
Optimised synthesis of the 15N-labelled insecticide phosmet (1)
✍ Scribed by Katrin Sinderhauf; Wolfgang Schwack
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- French
- Weight
- 80 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0022-2135
- DOI
- 10.1002/jlcr.842
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✦ Synopsis
Abstract
A simple strategy for the small‐scale synthesis of the ^15^N‐labelled insecticide phosmet has been developed, starting from ^15^N‐phthalimide‐K. Copyright © 2004 John Wiley & Sons, Ltd.
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## Abstract 5‐Phenyl‐1,2,4‐thiadiazole‐4‐^15^N and 3‐methyl‐5‐phenyl‐1,2,4‐thiadiazole‐4‐^15^N were synthesized from commercially available benazmide‐^15^N. The mass spectra and the ^1^H, ^13^C, and ^15^N‐nmr spectra of these compounds, which show various long‐range heteronuclear coupling with the
## Abstract The ^15^N chemical shifts and ^1^H^15^N and ^13^C^15^N coupling constants of nine monolabelled indazoles were measured and assigned. The experimental values are discussed in terms of the indazolic and iso‐indazolic structures, and compared with literature data for other related hetero