Total synthesis of optically active chan
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Yuusaku Yokoyama; Kazuhiro Kondo; Masako Mitsuhashi; Yasuoki Murakami
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Article
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1996
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Elsevier Science
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French
โ 221 KB
The total synthesis of optically active clianochvine-I, an ergot alkaloid, was accomplished using palladium-catalyzed intramoleeular cyclization (Heck reaction) as a key step. The conjugate ester (6) was obtained in 2 steps from optically active 4-bmmotryptophan (10), and the cyclization of 6 procee