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Opposite effects of halothane on guinea-pig ventricular action potential duration

✍ Scribed by Cécile Terrenoire; Vincent Piriou; Robert Bonvallet; Christophe Chouabe; Leon Espinosa; Oger Rougier; Yves Tourneur

Book ID
114012804
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
218 KB
Volume
390
Category
Article
ISSN
0014-2999

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The electrophysiological effects of urapidil, a new aradrenoceptor antagonist, were assessed in the reserpinized guinea-pig ventricular myocardium. Urapidil suppressed the maximal rate of rise (Vm~) of steady-state action potentials elicited by the fast responses at high concentrations independently