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Effect of Raised Extracellular Calcium on Characteristics of the Guinea-pig Ventricular Action Potential

✍ Scribed by Stewart P. Leitch; Hilary F. Brown

Book ID
115632117
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
166 KB
Volume
28
Category
Article
ISSN
0022-2828

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The electrophysiological effects of urapidil, a new aradrenoceptor antagonist, were assessed in the reserpinized guinea-pig ventricular myocardium. Urapidil suppressed the maximal rate of rise (Vm~) of steady-state action potentials elicited by the fast responses at high concentrations independently