✦ LIBER ✦

Open study of the safety and efficacy of a single oral dose of cefixime for the treatment of gonorrhea in pregnancy

✍ Scribed by Joseph M. Miller Jr.

Publisher: Hindawi Publishing Corporation
Year: 1997
Tongue: English
Weight: 42 KB
Volume: 5
Category: Article
ISSN: 1064-7449
DOI: 10.1002/(sici)1098-0997(1997)5:3<259::aid-idog12>3.0.co;2-n

No coin nor oath required. For personal study only.

✦ Synopsis

Objective: The intent of this study was to determine the efficacy and tolerance of single dose oral cefixime use in the treatment of pregnant women with endocervical gonococcal carriage.

Methods: A retrospective review of clinic records over a 3 year period identified patients treated with a single 400 mg dose of cefixime for gonorrhea during pregnancy. Side effects and subsequent gonococcal carriage were noted.

Results: Pregnant women (n = 102) treated with cefixime were reviewed. A cure rate of 95.2% was found. Side effects were reported in three patients: two had nausea and vomiting and one had diarrhea.

Conclusions: A single 400 mg oral dose of cefixime was effective for the treatment of gonorrhea and was well tolerated by the pregnant women.

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