Subcellular distribution of the insulin-
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Tiezheng Sun; Ernst B. Hunziker; Teresa I. Morales
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Article
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2008
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Elsevier Science
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English
β 147 KB
## Abstract The insulinβlike growth factor (IGF) is a major anabolic regulator in articular cartilage. The IGFβbinding proteins (IGFBPs) are increased during osteoarthritis (OA), but the function of the later proteins remains unknown. In general, the IGFBPs are pluripotential effectors capable of I