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Peri/nuclear localization of intact insulin-like growth factor binding protein-2 and a distinct carboxyl-terminal IGFBP-2 fragment in vivo

✍ Scribed by A. Hoeflich; R. Reisinger; B.S. Schuett; M.W. Elmlinger; V.C. Russo; G.A. Vargas; P.M. Jehle; H. Lahm; I. Renner-Müller; E. Wolf


Book ID
116289258
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
744 KB
Volume
324
Category
Article
ISSN
0006-291X

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We examined the distribution of insulin-like growth factor binding proteins (IGFBPs) in cultured neonatal mouse calvariae. IGFBP-3 and -4 were predominantly found in the conditioned medium. IGFBP-2 was partitioned between conditioned medium and bone and extracellular matrix (BECM), while intact (31