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Ontogeny of behavioral sensitization to cocaine

โœ Scribed by Hiroshi Ujike; Kazuo Tsuchida; Kazufumi Akiyama; Yutaka Fujiwara; Shigetoshi Kuroda


Book ID
113225900
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
645 KB
Volume
50
Category
Article
ISSN
0091-3057

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Sensitization to cocaine has been attributed to alterations in excitatory amino acid and dopamine neurotransmission in the mesolimbic system. The present study sought to determine whether inhibition of NAALADase, an enzyme that cleaves glutamate from the endogenous neuropeptide, N-acetyl-aspartyl-gl