Modulation of behavioral sensitization t
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Toni S. Shippenberg; William Rea; Barbara S. Slusher
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Article
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2000
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John Wiley and Sons
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English
β 88 KB
Sensitization to cocaine has been attributed to alterations in excitatory amino acid and dopamine neurotransmission in the mesolimbic system. The present study sought to determine whether inhibition of NAALADase, an enzyme that cleaves glutamate from the endogenous neuropeptide, N-acetyl-aspartyl-gl