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Behavioral sensitization to cocaine: cooperation between glucocorticoids and epinephrine

✍ Scribed by Inge E. M. de Jong; Peter J. Steenbergen; E. Ronald de Kloet


Publisher
Springer
Year
2009
Tongue
English
Weight
231 KB
Volume
204
Category
Article
ISSN
0033-3158

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Sensitization to cocaine has been attributed to alterations in excitatory amino acid and dopamine neurotransmission in the mesolimbic system. The present study sought to determine whether inhibition of NAALADase, an enzyme that cleaves glutamate from the endogenous neuropeptide, N-acetyl-aspartyl-gl