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Ongoing First-Line Studies of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Select Patient Populations

✍ Scribed by Pasi A. Jänne


Book ID
114473858
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
161 KB
Volume
32
Category
Article
ISSN
0093-7754

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## Abstract The syntheses and biological activities of some nitrostyrene derivatives of adenosine 5′‐glutarates, a novel class of selective, bi‐substrate‐type inhibitors of the EGF receptor protein tyrosine kinase with __IC__~50~ values around 1 μM. Only marginal inhibition of the tyrosine kinases