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One-step synthesis of 1,1-dimethyl and 1-spirocycloalkane-1,2,3,4-tetrahydro-.beta.-carbolines

โœ Scribed by Carrasco, N.; Urzua, A.; Cassels, B. K.


Book ID
125481714
Publisher
American Chemical Society
Year
1973
Tongue
English
Weight
286 KB
Volume
38
Category
Article
ISSN
0022-3263

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Stereospecific synthesis of trans-1,3-di
โœ Frank Ungemach; Mike DiPierro; Robert Weber; James M. Cook ๐Ÿ“‚ Article ๐Ÿ“… 1979 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 241 KB

The stereospecific synthesis of trans-1,3-disubstituted-1,2,3,4\_tetrahydro $-carbolines has been accomplished in good yield by a two step sequence which involves Pi&et-Spengler condensation of Nb-benzyltryptophan methyl: ester with aldehydes, followed by removal of the 2-benzyl moiety from the corr