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One-sample and two-sample analysis of heterogeneous person–time data in clinical trials

✍ Scribed by Jing Xu; Michael LaValley


Book ID
112183497
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
238 KB
Volume
11
Category
Article
ISSN
1539-1604

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This paper evaluates the loss of power of the simple and stratified logrank tests due to heterogeneity of patients in clinical trials and proposes a flexible and efficient method of estimating treatment effects adjusting for prognostic factors. The results of the paper are based on the analyses of s