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Sample size formula for joint modelling of longitudinal and time-to-event data in clinical trials

✍ Scribed by Matthew Powney,Paula Williamson,Ruwanthi Kolamunnage-Dona

Book ID: 126377084
Publisher: BioMed Central
Year: 2013
Tongue: English
Weight: 122 KB
Volume: 14
Category: Article
ISSN: 1468-6708
DOI: 10.1186/1745-6215-14-S1-O108

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## Abstract Shared random effects joint models are becoming increasingly popular for investigating the relationship between longitudinal and time‐to‐event data. Although appealing, such complex models are computationally intensive, and quick, approximate methods may provide a reasonable alternative