One-Pot Two-Steps Synthesis of 1,2-Diol
โ Scribed by Fringuelli, F.; Germani, R.; Pizzo, F.; Savelli, G.
- Book ID
- 120799078
- Publisher
- Taylor and Francis Group
- Year
- 1989
- Tongue
- English
- Weight
- 155 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0039-7911
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The reactions of ketones 1a -o, nitromethane 2, and a stoichiometric amount of piperidine 3a or ethylenediamine 3b in the presence of mercaptan 6a in THF or CH 3 CN solution give high yields of b-nitrosulfides 7a -o. The latter can be oxidized by 8a (m-CPBA or m-CPBA/AcOH) at 08C, 8b (H 2 O 2 /AcOH)
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Cerpegin 1 was synthesized in a one-pot reaction at room temperature catalysed by cesium carbonate with an overall of 75% yield. 3-Hydroxy-3-methyl-2-butanone 2 reacted with diethyl malonate 3 to give 2-ethoxycarbonyl-3,4,4-trimethyl-2-buten-4-olide 4. Then 4 with s-triazine gave to I,l-dimethylfuro