𝔖 Bobbio Scriptorium
✦   LIBER   ✦

One-pot, two-step enzymatic synthesis of amoxicillin by complexing with Zn2+

✍ Scribed by Ye-Wang Zhang; Rui-Jiang Liu; Xi-Ming Xu

Book ID
105952784
Publisher
Springer
Year
2010
Tongue
English
Weight
286 KB
Volume
88
Category
Article
ISSN
1432-0614

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

A two-step, one-pot enzymatic synthesis
A two-step, one-pot enzymatic synthesis of cephalexin from D-phenylglycine nitrile
✍ Margreth A. Wegman; Luuk M. van Langen; Fred van Rantwijk; Roger A. Sheldon πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 113 KB πŸ‘ 2 views

## Abstract A cascade of two enzymatic transformations is employed in a one‐pot synthesis of cephalexin. The nitrile hydratase (from __R. rhodochrous__ MAWE)‐catalyzed hydration of D‐phenylglycine nitrile to the corresponding amide was combined with the penicillin G acylase (penicillin amidohydrola

A one-pot, two step synthesis of 2,2-dis
A one-pot, two step synthesis of 2,2-disubstituted 1-nitroalkenes
✍ Yeong-Jiunn Jang; Wen-Wei Lin; Yuh-Kuo Shih; Ju-Tsung Liu; Ming-Hsing Hwang; Chi πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 303 KB

The reactions of ketones 1a -o, nitromethane 2, and a stoichiometric amount of piperidine 3a or ethylenediamine 3b in the presence of mercaptan 6a in THF or CH 3 CN solution give high yields of b-nitrosulfides 7a -o. The latter can be oxidized by 8a (m-CPBA or m-CPBA/AcOH) at 08C, 8b (H 2 O 2 /AcOH)