One-Pot, Three-Component Synthesis of 5-(Alkylimino)-2-(diethoxyphosphoryl)-2,5-dihydrofuran-3,4-dicarboxylates
✍ Scribed by Azizian, Javad; Ramazani, Ali; Haji, Mohammad; Azizkhani, Vahid
- Book ID
- 120462187
- Publisher
- Taylor and Francis Group
- Year
- 2011
- Tongue
- English
- Weight
- 277 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0039-7911
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📜 SIMILAR VOLUMES
## Abstract The zwitterionic 1:1 intermediates formed from alkyl isocyanides and acetylenic esters are trapped by alkyl bromides to form 5‐alkylimino‐2,5‐dihydrofuran‐3,4‐dicarboxylate in relatively good yields at room temperature under solventless conditions. Hydrolysis of these compounds by HCl (
## Abstract magnified image The reactive zwitterionic 1 : 1 intermediate **6** generated __in situ__ from the reaction between an isocyanide **2** and a dialkyl acetylenedicarboxylate (=dialkyl but‐2‐ynedioate) **3** was trapped by an __N__‐arylmaleimide or ‐phthalimide **4** to produce a highly f