ChemInform Abstract: One-Pot, Three-Component Synthesis of 5-(Alkylimino)-2- (diethoxyphosphoryl)-2,5-dihydrofuran-3,4-dicarboxylates.
β Scribed by Javad Azizian; Ali Ramazani; Mohammad Haji; Vahid Azizkhani
- Book ID
- 112043779
- Publisher
- John Wiley and Sons
- Year
- 2012
- Weight
- 24 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The zwitterionic 1:1 intermediates formed from alkyl isocyanides and acetylenic esters are trapped by alkyl bromides to form 5βalkyliminoβ2,5βdihydrofuranβ3,4βdicarboxylate in relatively good yields at room temperature under solventless conditions. Hydrolysis of these compounds by HCl (
An Efficient One-Pot Synthesis of Dialkyl 2,5-Dihydrofuran-2,3dicarboxylates Mediated by Vinyltriphenylphosphonium Salt. -Functionalized 2,5-dihydrofurans (III) (9 examples) are prepared in fairly good yields by PPh 3 -mediated reaction of dialkyl acetylenedicarboxylates (I) with 2-hydroxyketones (I