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One-Pot, Three-Component Coupling Approach to the Synthesis of α–Iminocarboxamides

✍ Scribed by Masui, Hisashi; Fuse, Shinichiro; Takahashi, Takashi


Book ID
118007220
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
312 KB
Volume
14
Category
Article
ISSN
1523-7060

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A very mild, efficient and simple method for the synthesis of tertiary a-amino phosphonates is reported by reaction of an aldehyde, a secondary amine and trialkylphosphite in ethereal solution of lithium perchlorate, LPDE, at ambient temperature with high yields.