One-Pot Synthesis of Triazoloquinazolinones via Copper- Catalyzed Tandem Click and Intramolecular CH Amidation
✍ Scribed by Selvaraju, Manikandan; Sun, Chung-Ming
- Book ID
- 121651239
- Publisher
- John Wiley and Sons
- Year
- 2014
- Tongue
- English
- Weight
- 506 KB
- Volume
- 356
- Category
- Article
- ISSN
- 1615-4150
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## Abstract A simple, practical, and highly efficient copper‐catalyzed one‐pot synthesis of imidazo/benzoimidazoquinazolinones has been developed. The procedure is based on a sequential copper‐catalyzed Ullmann‐type N‐arylation and aerobic oxidative intramolecular CH amidation. This method should
## Abstract A robust one‐pot process has been developed for the synthesis of a variety of polycyclic indole skeletons __via__ a consecutive sequence of hydroamidation and palladium‐catalyzed annulation, from inexpensive 2‐chloroanilines bearing tethered acetylenes.