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Copper-Catalyzed One-Pot Synthesis of Imidazo/Benzoimidazoquinazolinones by Sequential Ullmann-Type Coupling and Intramolecular CH Amidation

✍ Scribed by Hao Xu ; Prof. Dr. Hua Fu


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
302 KB
Volume
18
Category
Article
ISSN
0947-6539

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✦ Synopsis


Abstract

A simple, practical, and highly efficient copper‐catalyzed one‐pot synthesis of imidazo/benzoimidazoquinazolinones has been developed. The procedure is based on a sequential copper‐catalyzed Ullmann‐type N‐arylation and aerobic oxidative intramolecular CH amidation. This method should provide a new and useful strategy for construction of N‐heterocycles.