𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Oncolytic adenoviral vector carrying the cytosine deaminase gene for melanoma gene therapy

✍ Scribed by Liu, Y; Deisseroth, A


Book ID
110019362
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
301 KB
Volume
13
Category
Article
ISSN
0929-1903

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Gene therapy for prostate cancer using t
✍ Tohru Miyagi; Dr. Kiyoshi Koshida; Osamu Hori; Hiroyuki Konaka; Hiroaki Katoh; Y πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 204 KB

## Abstract ## Background Cytosine deaminase (CD) activates prodrug 5‐FC to 5‐FU and is used for suicide gene therapy (the CD/5‐FC system). __E. coli__ uracil phosphoribosyltransferase (UPRT) is a pyrimidine salvage enzyme that directly converts 5‐FU into 5‐fluorouridine monophosphate and improves

Cytosine deaminase gene as a potential t
✍ Rowley, Simon; Lindauer, Marcus; Gebert, Johannes F.; Haberkorn, Uwe; Oberdorfer πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 632 KB

The bacterial enzyme cytosine deaminase (CD) catalyzes the conversion of 5-fluorocytosine (5-FC) to the lethal 5-fluorouracil (5-Fu) and so provides a useful system for selective killing of gene-modified mammalian tumor cells. Cloning of the CD gene from Escherichiu coli and expression in human tumo