Oncogenes
โ Scribed by John Paul
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 696 KB
- Volume
- 143
- Category
- Article
- ISSN
- 0022-3417
No coin nor oath required. For personal study only.
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Advances are being made at an increasing rate towards an understanding of the role of cellular oncogenes in the normal and transformed cell. This review highlights a number of studies looking at the role of these genes in the carcinogenic process using in vivo and in vitro systems. Current Opinion
Currently, the most widely accepted paradigm of oncogenesis is based on the concept of a balance between positive-and negative-growth regulatory mechanisms. Aberrations in these regulatory pathways can lead to a transformed phenotype, seen clinically as tumorigenesis. In vivo, there may be additiona