Patients with rheumatoid arthritis who are unresponsive to antiinflammatory drugs and slow-acting agents such as gold, hydroxychloroquine, and Dpenicillamine, pose a therapeutic challenge. This report details the effectiveness of weekly intravenous methotrexate in 14 such patients resistant to stand
On the treatment of rheumatoid arthritis with m&ms (motrin &methotrexate)
β Scribed by Israeli A. Jaffe
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 128 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## Objective There is evidence supporting a therapeutic range for methotrexate polyglutamate (MTXGlu) concentrations in the treatment of rheumatoid arthritis (RA). Knowledge of the pharmacokinetics of MTXGlu~1β5~ is required for optimal timing of blood sampling. The aim of this study w
## Objective: Recently, new treatment options for rheumatoid arthritis (ra) patients with an inadequate response to methotrexate (mtx) have become available. given the wide variability in efficacy and costs among these different treatment options, we sought to determine their cost-effectiveness (ce
Objective. To evaluate the influence of food on the bioavailability of an oral dose of methotrexate in patients with rheumatoid arthritis. Methods. Methotrexate (15 mg) was given intravenously and orally, with or without a meal, to 10 patients. Blood samples were drawn at specific intervals to eval