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On the Substrate Specificity of Dehydration by Lacticin 481 Synthetase

✍ Scribed by Zhang, Xingang; van der Donk, Wilfred A.

Book ID
126975311
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
65 KB
Volume
129
Category
Article
ISSN
0002-7863

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## Abstract **One enzyme, many substrates**. The substrate specificity of a lantibiotic biosynthetic enzyme, lacticin 481 synthetase, was probed by using synthetic prepeptides containing a variety of nonproteinogenic amino acids, including unnatural α‐amino acids, β‐amino acids, D‐amino acids, and