This report details the influence of the time lapse and surface area size of intravitreal copper foreign bodies on the etectroretinogram (ERG) and the recovery of the potentials after removal of the particles. Pure copper wires were implanted temporarily into the vitreous body of rat eyes in the are
On the recovery of the electroretinogram after removal of intravitreal zinc particles
โ Scribed by Joachim G. H. Schmidt; Christoph Nies; Regina Mansfeld-Nies
- Book ID
- 104640048
- Publisher
- Springer-Verlag
- Year
- 1987
- Tongue
- English
- Weight
- 474 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0012-4486
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โฆ Synopsis
The influence of intravitreal zinc particles (1.3 mm 2) in the eyes of rats caused the amplitudes of the electroretinogram to decrease to about 50% of the initial values within 24 hours, whereas the prolongation of the peak times began only on the third day after particle implantation. The removal of the zinc particles after 30 days led to only partial recovery of the amplitudes, whereas the peak times reached normal values. Dissociated behaviour of the amplitudes and peak times as described here was not found in earlier experiments with intravitreal iron, copper or lead particles of the same size.
The extraction of intravitreal zinc particles (1.3 mm 2) one day after implantation resulted in a recovery of the amplitudes up to 85%.
๐ SIMILAR VOLUMES
Lead particles (1.4 mm2) were implanted into the vitreous body of rats (16 animals) for 10 days and the recovery rate of the ERG was measured over an observation time of 190 days. After extraction of the lead particles the a- and b-wave amplitudes show a recovery from about 60% to 87% in comparison
The electroretinogram (ERG) was recorded 20 times over a period of 360 days in 26 albino-rats with implanted intravitreal iron wires ranging in size between 0.15 and 1.2 mm 2. Results: (i) The a-and b-wave amplitudes decreased rapidly within one day after iron wire implantation. During the following