Surface area sizes of intravitreal iron wires: Their effects on the electroretinograms of rats

✍ Scribed by Joachim G. H. Schmidt; Michael Max

• Book ID: 104640654
• Publisher: Springer-Verlag
• Year: 1987
• Tongue: English
• Weight: 472 KB
• Volume: 67
• Category: Article
• ISSN: 0012-4486
• DOI: 10.1007/bf00144280

✦ Synopsis

The electroretinogram (ERG) was recorded 20 times over a period of 360 days in 26 albino-rats with implanted intravitreal iron wires ranging in size between 0.15 and 1.2 mm 2. Results: (i) The a-and b-wave amplitudes decreased rapidly within one day after iron wire implantation. During the following week the amplitudes recovered to some extent. In the course of the next few months the a-and b-wave amplitudes of the eyes implanted with the largest iron wires (1.2 mm 2) decreased steadily to about 20% by the end of the observation time, whereas in the groups containing smaller iron wires the electroretinographic changes were limited. (ii) Implantation of equally-sized glass splinters reduced the a-and b-wave amplitudes to 65-75 % in comparison to the intact fellow eye. Fast recovery of both potentials to 83-93% followed within two weeks. The mean values of the a-wave amplitudes reached nearly 100%, those of the b-wave 90-95% in the next month.