Kinetic studies established that the monomethylation of a primary amine leads to significantly higher reaction rates with glycidyl ethers. The relative rates for approximately 25 amines were determined in an alcohol solvent under pseudo-firstorder conditions (excess epoxy). The rates were referenced
โฆ LIBER โฆ
On the reaction of glycidol with a secondary amine
โ Scribed by Ewa Witek; Andrzej Kochanowski; Edgar Bortel
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 74 KB
- Volume
- 21
- Category
- Article
- ISSN
- 1022-1336
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The title reactions are subjected to a kinetic analysis in ethanol-water, at 44 wt% ionic strength 0.2 (KCl). With a large excess of amine over the substrate, pseudo-first-25.0ะC, order rate coefficients are obtained, which are linearly dependent on the amine concen-(k ) obs tration. The nucleophili