On the pathological progression of Huntington's disease
β Scribed by Katarzyna A. Sieradzan; David M. A. Mann
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 111 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
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## Abstract The objective of this study was to examine the relationship between CAG repeat length (CAGn) and clinical progression in patients with Huntington's disease (HD). There are conflicting reports about the relationship between CAGn and clinical progression of HD. We conducted an analysis of
## Abstract Huntington's disease (HD) is a neurodegenerative disease caused by a cytosine adenosine guanine (CAG) expansion in the __huntingtin__ gene. The length of the triplet repeat is the most important factor in determining age of onset and the severity of the disease, but substantial variabil
## Abstract The purpose of this study was to systematically assess the impact of Huntington's disease (HD) on patients' healthβrelated quality of life (QOL). Seventyβseven patients with a clinically confirmed diagnosis of HD were interviewed by means of the Sickness Impact Profile (SIP). Additional