✦ LIBER ✦

Impact of Huntington's disease on quality of life

✍ Scribed by D.I. Helder; A.A. Kaptein; G.M.J. van Kempen; J.C. van Houwelingen; R.A.C. Roos

Publisher: John Wiley and Sons
Year: 2001
Tongue: English
Weight: 77 KB
Volume: 16
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.1056

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The purpose of this study was to systematically assess the impact of Huntington's disease (HD) on patients' health‐related quality of life (QOL). Seventy‐seven patients with a clinically confirmed diagnosis of HD were interviewed by means of the Sickness Impact Profile (SIP). Additional data were gathered on patients' motor performance by means of the motor section of the Unified Huntington Disease Rating Scale (UHDRS), and cognitive performance by means of the Mini‐Mental State (MMS). Patients had high scores on the SIP subscales, indicating moderate to severe functional impairment. Total Motor Score (TMS), MMS scores, and the duration of HD were significantly correlated with patients' scores on the SIP, and predicted a significant amount of variance of the Physical Dimension of the SIP, but not of the Psychosocial Dimension. We conclude that HD has a great impact on patients' physical and psychosocial well‐being, the latter being more severely affected. Implications for further research and clinical practice are discussed. © 2001 Movement Disorder Society.

📜 SIMILAR VOLUMES

Patient and caregiver quality of life in

Patient and caregiver quality of life in Huntington's disease

✍ Rebecca E. Ready; Melissa Mathews; Anne Leserman; Jane S. Paulsen 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 67 KB 👁 1 views

## Abstract Little is known about subjective perceptions of quality of life (QOL) in Huntington's disease (HD). The current study determined correlates of patient and caregiver QOL and assessed change over time. Participants were 22 patient‐caregiver dyads, who rated QOL at baseline and 6 months la

Impact of the motor complications of Par

Impact of the motor complications of Parkinson's disease on the quality of life

✍ Stéphane Chapuis; Lemlih Ouchchane; Olivier Metz; Laurent Gerbaud; Franck Durif 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 86 KB 👁 1 views

## Abstract The impact of motor complications of Parkinson's disease (PD), especially levodopa‐induced dyskinesias, on quality of life (QL) was studied in 143 patients with PD. All were evaluated on the Hoehn and Yahr (H&Y) scale, and the Motor part of the Unified Parkinson's Disease Rating Scale (

What is the impact of education on Hunti

What is the impact of education on Huntington's disease?

✍ Jose Luis López-Sendón; Ana Royuela; Patricia Trigo; Michael Orth; Herwig Lange; 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 188 KB 👁 1 views

## Abstract Huntington's disease (HD) is a neurodegenerative disease caused by a cytosine adenosine guanine (CAG) expansion in the __huntingtin__ gene. The length of the triplet repeat is the most important factor in determining age of onset and the severity of the disease, but substantial variabil

Health-related quality of life in Huntin

✍ Aileen K. Ho; Abigail S. Gilbert; Sarah L. Mason; Anna O. Goodman; Roger A. Bark 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 62 KB 👁 1 views

## Abstract The aim of this article was to determine which aspects of Huntington's disease (HD) are most important with regard to the health‐related quality of life (HrQOL) of patients with this neurodegenerative disease. Seventy patients with HD participated in the study. Assessment comprised the

Impact of cervical dystonia on quality o

Impact of cervical dystonia on quality of life

✍ Laura Camfield; Yoav Ben-Shlomo; Thomas T. Warner 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 305 KB 👁 1 views

We studied the effect of cervical dystonia on quality of life in a cohort of 289 patients by using a generic health status measurement scale (SF36). Cervical dystonia had a significant negative impact on quality of life compared with age-matched general population data. This negative impact was comp

Factors impacting on quality of life in

Factors impacting on quality of life in Parkinson's disease: Results from an international survey

✍ The Global Parkinson's Disease Survey (GPDS) Steering Committee 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 161 KB 👁 1 views

## Abstract Current management guidelines for the treatment of patients with Parkinson's disease (PD) are limited due to the lack of knowledge of factors that influence health‐related quality of life (HRQL). To assess the HRQL of people with PD, and to systematically identify and evaluate those fac