BIRCH' demonstrated in 1950 that a steroidal a,p-unsaturated ketone (I) may be deconjugated to its p,y-unsaturated ketone isomer (III) by irreversible protonation of the conjugate anion (II), however, the requisite anion has been prepared only by indirect means (e.g. through the enol acetate, 132 fr
✦ LIBER ✦
On the optical activity of α,β-unsaturated ketones.
✍ Scribed by H. Zipper; C.H. Robinson
- Publisher
- Elsevier Science
- Year
- 1969
- Tongue
- French
- Weight
- 37 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0040-4020
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## Abstract Eleven structurally different α, β‐unsaturated ketones were subjected to the __Clemmensen__ reduction under anhydrous conditions using amalgamated zinc, hydrogen chloride in a solution of ethyl ether, and acetic anhydride. In all cases but one the formation of cyclopropyl acetates was o