A mild method for the selective reduction of a,b-unsaturated ketones is reported. The process described herein involves, as the active species, the low-valent titanium complex Cp 2 TiCl.
Novel reduction of α-bromo-α,β-unsaturated ketones. Selective synthesis of β,γ-unsaturated ketones
✍ Scribed by Toshikazu Hirao; Toshio Masunaga; Ken-ichiro Hayashi; Yoshiki Ohshiro; Toshio Agawa
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- French
- Weight
- 121 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
Selective bromination of a&unsaturated ketones has been achieved by the action of 2,4,4,6tetrabromocyclohexa-2$dienone. The stereochemistry, conformation and relative stability of the bromination products of some steroidic unsaturated ketones have been also determined.
## Abstract Eleven structurally different α, β‐unsaturated ketones were subjected to the __Clemmensen__ reduction under anhydrous conditions using amalgamated zinc, hydrogen chloride in a solution of ethyl ether, and acetic anhydride. In all cases but one the formation of cyclopropyl acetates was o