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On the mode of selection in escherichia coli

✍ Scribed by Kazuhiko Kosuda

Publisher
Springer Netherlands
Year
1981
Tongue
English
Weight
416 KB
Volume
55
Category
Article
ISSN
0016-6707

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✦ Synopsis

Selection experiments between a lac+wild type and a lac-mutant of Escherichia co/i were conducted using a serial transfer procedure at two levels of total sugar concentration, i.e., 0.750 g/l and 1.0 g/l, The relative frequencies of both genotypes were assayed every 48 hours, at the time of transfer and the frequency changes were followed for about four weeks. The frequency of lac-decreased steadily and it was eventually eliminated from the mixed populations in all replicate cultures. The regression of logit pt was shown to be not linear but curvilinear, indicating that fitness differentials are frequency-dependent.

The selection is also probably density-dependent. In&oducGon

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