𝔖 Bobbio Scriptorium
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On the Mechanism of Toxin Resistance in Cell Variants Resistant to Abrin and Ricin

✍ Scribed by Sjur OLSNES; Karin REFSNES


Book ID
115116766
Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
907 KB
Volume
88
Category
Article
ISSN
1432-1327

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πŸ“œ SIMILAR VOLUMES


Mechanism of resistance to ricin toxin i
✍ Nicolson, Garth L. ;Poste, George πŸ“‚ Article πŸ“… 1978 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 845 KB

The role of impaired toxin uptake in conferring cellular resistance t o the plant toxin RCAII (ricin) has been examined using a murine BW5 147 lymphoma line and a toxin-resistant variant (BW5 147RicR.3) selected by repeated exposure t o RCAII. The toxin-resistant variant is 250 times more resistant

Properties and action mechanism of the t
✍ Olsnes, Sjur ;Sandvig, Kirsten ;Eiklid, Kristin ;Pihl, Alexander πŸ“‚ Article πŸ“… 1978 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 604 KB

The toxic lectin modeccin, which inhibits protein synthesis in eukaryotic cells, is cleaved upon treatment with 2-mercaptoethanol into two peptide chains which move in polyacrylamide gels at rates corresponding to molecular weights 28,000 and 38,000. After reduction, the toxin loses its effect on ce