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On the distributions of spontaneous chromosomal aberrations in human peripheral blood lymphocytes in culture

โœ Scribed by M.A. Bender; R.J. Preston; R.C. Leonard; B.E. Pyatt; P.C. Gooch


Book ID
113255432
Publisher
Elsevier Science
Year
1990
Weight
356 KB
Volume
244
Category
Article
ISSN
0165-7992

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Post-treatment of mutagen-treated human peripheral lymphocytes with a single-strand specific endonuclease from Neurospora crassa leads to a significant elevation of the rate of structural chromosomal aberrations. Our results indicate that DNA double-strand breaks (DSB) are ultimate lesions for the f