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Spontaneous chromosomal aberration levels in human peripheral lymphocytes

✍ Scribed by B. Ivanov; L. Praskova; M. Mileva; M. Bulanova; I. Georgieva


Book ID
113191407
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
298 KB
Volume
52
Category
Article
ISSN
0027-5107

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Post-treatment of mutagen-treated human peripheral lymphocytes with a single-strand specific endonuclease from Neurospora crassa leads to a significant elevation of the rate of structural chromosomal aberrations. Our results indicate that DNA double-strand breaks (DSB) are ultimate lesions for the f