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No cyclosporin-induced chromosomal aberrations in human peripheral blood lymphocytes in vitro

โœ Scribed by T.S.B. Zwanenburg; A. Cordier

Book ID
119093892
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
339 KB
Volume
320
Category
Article
ISSN
0165-1218

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Post-treatment of mutagen-treated human peripheral lymphocytes with a single-strand specific endonuclease from Neurospora crassa leads to a significant elevation of the rate of structural chromosomal aberrations. Our results indicate that DNA double-strand breaks (DSB) are ultimate lesions for the f