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The restriction endonuclease Alu I induces chromosomal aberrations in human peripheral lymphocytes in vitro

✍ Scribed by G. Obe; R. Jonas; S. Schmidt

Book ID
113192968
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
248 KB
Volume
163
Category
Article
ISSN
0027-5107

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Post-treatment of mutagen-treated human peripheral lymphocytes with a single-strand specific endonuclease from Neurospora crassa leads to a significant elevation of the rate of structural chromosomal aberrations. Our results indicate that DNA double-strand breaks (DSB) are ultimate lesions for the f