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On practical aspects of the use of anti-influenza drugs

โœ Scribed by Hannoun, C.


Book ID
122667797
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
78 KB
Volume
143
Category
Article
ISSN
0923-2516

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The anti-HIV nucleotide analogue PMPA can be prepared on a kilogram-scale by a three step sequence: i) condensation of adenine with (R)-propylene carbonate, ii) alkylation of the resulting (R)-9-(2-hydroxypropyl)adenine with diethyl p-toluenesulfonyloxymethanephosphonate using lithium tert-butoxide