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Omeprazole does not affect measured CYP3A4 activity using the erythromycin breath test [letter]

โœ Scribed by T Tateishi; SG Graham; Y Krivoruk; AJ Wood


Book ID
119833549
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
410 KB
Volume
40
Category
Article
ISSN
0306-5251

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Assessment of ifosfamide pharmacokinetic
โœ Rashmi Chugh; Thomas Wagner; Kent A. Griffith; Jeremy M.G. Taylor; Dafydd G. Tho ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 190 KB

## Abstract ## BACKGROUND. Ifosfamide is a chemotherapeutic agent that requires cytochrome P450 3A (CYP3A) for bioactivation and metabolism. To the authors' knowledge, the correlation between dose, pharmacokinetics, CYP3A, and toxicity has not been fully evaluated. A randomized Phase II trial was