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Oligonucleotide modelization of DNA-platinum complexes interactions.

✍ Scribed by J.C. Chottard

Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
82 KB
Volume
43
Category
Article
ISSN
0162-0134

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πŸ“œ SIMILAR VOLUMES

DNA-platinum interactions. Characterizat
DNA-platinum interactions. Characterization of solid DNAξ—ΈK2[PtCl4 complexes
✍ J.-P. Macquet; T. Theophanides πŸ“‚ Article πŸ“… 1976 πŸ› Elsevier Science 🌐 English βš– 564 KB

## A specific reaction of cis-dichlorodiammineplatinum-(II), cis-Pt(NH3& with the GC planes of DNA is reported. This interaction is localized on the N,(G) and the O,(G) sites forming a chelate without proton liberation. On the other hand, the reaction of Kz [PtCl,] with DNA (41% or 72% GC) is also s