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Oligonucleosides: synthesis of a novel methylhydroxylamine-linked nucleoside dimer and its incorporation into antisense sequences

โœ Scribed by Vasseur, Jean Jacques; Debart, Francoise; Sanghvi, Yogesh S.; Cook, P. Dan


Book ID
127218719
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
323 KB
Volume
114
Category
Article
ISSN
0002-7863

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The synthesis of the aryl nucleoside analogue P2'-deoxy-D-ribofuranosyl-l'-N-pyrenylcarboxamide (4) is described. This compound can be converted into a phosphoranudite reagent and used in solid phase oligonucleotide synthesis.