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Oligodeoxynucleotides containing C-5 propyne analogs of 2′-deoxyuridine and 2′-deoxycytidine

✍ Scribed by Brian C. Froehler; Shalini Wadwani; Terry J. Terhorst; Sonja R. Gerrard

Book ID: 108380377
Publisher: Elsevier Science
Year: 1992
Tongue: French
Weight: 207 KB
Volume: 33
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)79079-4

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## Abstract [2‐^14^C]5‐Allyl‐2′‐deoxyuridine was synthesized directly from [2‐^14^C]2′‐deoxyuridine using mercury, palladium, and 3‐chloropropene. [2‐^14^C]5‐Propyl‐2′‐deoxyuridine was obtained by hydrogenation of the [^14^C]5‐allyl‐2′‐deoxy‐uridine. Advantages of the synthetic method and its appli