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The Cyclobutane Dimers of 2′-Deoxyuridine, 2′-Deoxycytidine, 5-Methyl-2′-Deoxycytidine and 5-Bromo-2′-Deoxyuridine

✍ Scribed by Martin D. Shetlar; Janet Chung

Book ID
114897522
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
288 KB
Volume
88
Category
Article
ISSN
0031-8655

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a b s t r a c t 5-Hydroxymethylcytosine has recently been characterized as the 'sixth base' in human DNA. To enable research on this DNA modification, we report an improved method for the synthesis of 5-hydroxymethyl-2 0 -deoxycytidine ( 5-HOMe dC) phosphoramidite for site-specific incorporation int