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Olefin cross-metathesis based approach for the stereoselective total synthesis of (+)-cardiobutanolide

✍ Scribed by Palakodety Radha Krishna; E. Shiva Kumar

Publisher: Elsevier Science
Year: 2009
Tongue: French
Weight: 225 KB
Volume: 50
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2009.09.077

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✦ Synopsis

Olefin cross-metathesis approach to (+)-cardiobutanolide has been achieved starting from D-mannitol utilizing Sharpless kinetic resolution and Sharpless asymmetric dihydroxylation.

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