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Sequential Cross-Metathesis/Phosphorus-Based Olefination: Stereoselective Synthesis of 2,4-Dienoates.

✍ Scribed by Tapas Paul; Rodrigo B. Andrade


Publisher
John Wiley and Sons
Year
2007
Weight
42 KB
Volume
38
Category
Article
ISSN
0931-7597

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One-pot sequential cross-metathesis/hydr
✍ Tapas Paul; Gopal Sirasani; Rodrigo B. Andrade πŸ“‚ Article πŸ“… 2008 πŸ› Elsevier Science 🌐 French βš– 149 KB

Several di-and trisubstituted primary (E)-allylic alcohols have been prepared from the corresponding terminal olefins in a highly stereoselective manner (>20:1 E/Z) by sequencing olefin cross-metathesis (CM) with hydride reduction (DIBAL-H) in good yields utilizing only commercially available reagen