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O6-Alkylguanine-DNA alkyltransferase activity of human malignant glioma and its clinical implications

✍ Scribed by Takuhiro Hotta; Yuji Saito; Hiroshi Fujita; Takashi Mikami; Kaoru Kurisu; Katsuzo Kiya; Tohru Uozumi; Gohei Isowa; Kanji Ishizaki; Mitsuo Ikenaga


Publisher
Springer US
Year
1994
Tongue
English
Weight
475 KB
Volume
21
Category
Article
ISSN
0167-594X

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## Abstract __O__^6^‐Alkylguanine‐DNA alkyltransferase (ATase) activity was determined in crude sonicates of tissues obtained from the F2 offspring of human ATase transgenic founder mice. In certain cases, samples were analyzed both before and after administration of zinc sulfate in the drinking wa