l?REVIOUSLY (1, 2) we have shown that N-oarboxy-a-amino acid anhydrides reaot with hydrooh+orides of amines to yield amino acid amides, aminohydroxemio acids and amidooxy-peptides. This reaotion was then applied to hydrochlorides of hydroxylamine and of N-alkyl and N,N-dialkyl
โฆ LIBER โฆ
O to N migration in reactions of O-substituted hydroxylamines
โ Scribed by Carey, Francis A.; Hayes, Larry J.
- Book ID
- 125991176
- Publisher
- American Chemical Society
- Year
- 1970
- Tongue
- English
- Weight
- 275 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0002-7863
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Abstruct : Treatment of &,P(O)Cl with MesSiNI-IOSiM~ gives Pr$P(0)NHOSiMes. which is desilylated by methanol giving P&P(O)NHOH. The 0-p-nitrobenz.enesulphonyI derivative of this rearranges with KOBu' in BuYIH, an isopropyl group migrating from P to N and the phosphonamidate R'P(O)(OBu?NIIpi being fo