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Active α-aminoacyl O-derivatives of N-substituted hydroxylamine. O to N migration and a method for peptide synthesis

✍ Scribed by Shmuel Bittner; Yehuda Knobler; Max Frankel

Publisher: Elsevier Science
Year: 1965
Tongue: French
Weight: 210 KB
Volume: 6
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)89934-7

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✦ Synopsis

l?REVIOUSLY (1, 2) we have shown that N-oarboxy-a-amino acid anhydrides reaot with hydrooh+orides of amines to yield amino acid amides, aminohydroxemio acids and amidooxy-peptides. This reaotion was then applied to hydrochlorides of hydroxylamine and of N-alkyl and N,N-dialkyl

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